Long Term Evaluation of Biodegradation and Biocompatibility In-Vivo the Mg-0.5Ca-xZr Alloys in Rats
| Autor: | Madalina Elena Henea, Bogdan Istrate, Iuliana Mihai, Eusebiu-Viorel Sindilar, Sorin Aurelian Pasca, Corneliu Munteanu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Biocompatibility General Chemical Engineering 0206 medical engineering technology industry and agriculture 02 engineering and technology Biodegradation 021001 nanoscience & nanotechnology Condensed Matter Physics Biocompatible material equipment and supplies 020601 biomedical engineering Biodegradable polymer biodegradation Inorganic Chemistry biocompatibility In vivo Metallic materials lcsh:QD901-999 General Materials Science Implant Mg-0.5Ca-xZr alloys lcsh:Crystallography 0210 nano-technology Biomedical engineering |
| Zdroj: | Crystals, Vol 11, Iss 54, p 54 (2021) Crystals Volume 11 Issue 1 |
| ISSN: | 2073-4352 |
| Popis: | Biodegradable alloys in Mg have the advantages of traditional metallic materials and those of biodegradable polymers with superior strength, lower density and ideal rigidity for fixing bone fractures. The biocompatibility and biodegradability of the five concentrations of Mg-0.5Ca-xZr alloys used were assessed using clinical and laboratory examinations that followed over time: tissue reaction, histological and imaging (RX, CT and SEM) evolution at 1, 2, 4 and 8 weeks after implant. The main purpose of this study was to investigate in vivo the long-term effect of Mg-0.5Ca-xZr alloys in rats. The results confirmed that Mg-0.5Ca-xZr alloys are biocompatible and biodegradable and are recommended to be used as possible materials for new orthopedics devices. |
| Databáze: | OpenAIRE |
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