Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea

Autor: Yi, Hwajung, Lee, Joo-Yeon, Hong, Eun-Hye, Kim, Mi-Seon, Kwon, Donghyok, Choi, Jang-Hoon, Choi, Woo-Young, Kim, Ki-Soon, Lee, Jong-Koo, Oh, Hee-Bok, Kang, Chun
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Male
Epidemiology
viruses
lcsh:Medicine
neuraminidase
medicine.disease_cause
Disease Outbreaks
chemistry.chemical_compound
Influenza A Virus
H1N1 Subtype
Pandemic
CME
Influenza A virus
Molecular Epidemiology
biology
H1N1
Dispatch
virus diseases
Middle Aged
Infectious Diseases
Child
Preschool
Human mortality from H5N1
Female
Microbiology (medical)
Oseltamivir
oseltamivir
Molecular Sequence Data
Antiviral Agents
Virus
Article
Microbiology
lcsh:Infectious and parasitic diseases
Viral Proteins
antiviral resistance
Drug Resistance
Viral
Influenza
Human
Republic of Korea
medicine
Humans
lcsh:RC109-216
hemagglutinin
pandemic
lcsh:R
Infant
Virology
Influenza A virus subtype H5N1
Influenza
respiratory tract diseases
chemistry
Amino Acid Substitution
biology.protein
Neuraminidase
Transmission and infection of H5N1
Zdroj: Emerging Infectious Diseases, Vol 16, Iss 12, Pp 1938-1942 (2010)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient.
Databáze: OpenAIRE
Externí odkaz: