Development of antiviral therapy for severe acute respiratory syndrome

Autor: Martin Michaelis, Gerold Hoever, Wolfgang Preiser, Hans Wilhelm Doerr, Jindrich Cinatl
Rok vydání: 2005
Předmět:
Zdroj: Antiviral Research
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2005.03.002
Popis: A new disease, the severe acute respiratory distress syndrome (SARS), caused by the SARS coronavirus (SARS-CoV), emerged at the beginning of 2003 and rapidly spread throughout the world. Although the disease had disappeared in June 2003 its re-emergence cannot be excluded. The development of vaccines against SARS-CoV may take years. Therefore, the availability of effective antiviral drugs against SARS-CoV may be crucial for the control of future SARS outbreaks. In this review, experimental and clinical data about potential anti-SARS drugs is summarised and discussed. Animal model studies will be needed to help to determine which interventions warrant controlled clinical testing.
Databáze: OpenAIRE