Is cancer an autoimmune process dependent on anti-apoptotic autoantibodies?

Autor:	Michel D. Kazatchkine, Y Bar-Dayan, Yehuda Shoenfeld, Srini V. Kaveri
Rok vydání:	2000
Předmět:	biology business.industry Autoantibody Cancer Apoptosis General Medicine medicine.disease_cause medicine.disease Autoimmune Diseases Autoimmunity Pathogenesis Autoimmune Process Neoplasms Immunology biology.protein Humans Medicine Antibody business Carcinogenesis Autoantibodies
Zdroj:	Medical Hypotheses. 55:103-108
ISSN:	0306-9877
DOI:	10.1054/mehy.1999.1035
Popis:	Dysregulated apoptosis is a potentially important mechanism in the pathogenesis of cancer. Autoantibodies, which inhibit apoptosis, have recently been identified in patients with malignant diseases. We suggest that such inhibitory autoantibodies participate in tumorigenesis. These views may provide a basis for the increased incidence of cancer in patients with autoimmune diseases and have novel therapeutic implications for cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2977183e41d600512ad7dfc8f0d54ca https://doi.org/10.1054/mehy.1999.1035 Zobrazit plný text záznamu Full Text from ScienceDirect