N-terminal proatrial natriuretic peptide predicts two-year remodelling in patients with acute transmural myocardial infarction
| Autor: | Christian Hall, Terje Skjærpe, Torstein Hole |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Myocardial Infarction Independent predictor Venous flow Combinatorics Ventricule gauche Internal medicine medicine Humans Left ventricular dilatation In patient Diastolic function Protein Precursors N-terminal proatrial natriuretic peptide Ventricular Remodeling business.industry Middle Aged Echocardiography Doppler Cardiology Female Myocardial disease Cardiology and Cardiovascular Medicine business Atrial Natriuretic Factor Biomarkers |
| Zdroj: | European Heart Journal. 25:416-423 |
| ISSN: | 0195-668X |
| Popis: | Aims To evaluate whether baseline N-terminal proatrial natriuretic peptide (Nt-proANP) or Doppler echocardiographic parameters could predict two-year left ventricular remodelling after acute myocardial infarction in patients without heart failure. Methods and results Seventy-one patients were followed with Doppler echocardiographic examinations at baseline, 3 months, 1 and 2 years, and Nt-proANP was measured at baseline and 3 months. After 2 years there was a significant increase in end-diastolic volume index of 11% (\batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(p=0.006\) \end{document}) and end-systolic volume index of 14% (\batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(p=0.03\) \end{document}), and no change in ejection fraction. This remodelling was confined to 12 patients (17%) with a significant increase in end-diastolic volume index above 20 ml/m2. Baseline Nt-proANP (\batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(p{ |
| Databáze: | OpenAIRE |
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