Reoperation for locally recurrent breast cancer in patients previously treated with conservative surgery
| Autor: | B Salvadori, F. Cusumano, S. Andreola, Rosalba Miceli, R. Zucali, Umberto Veronesi, A. R. Conti, Ettore Marubini |
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| Rok vydání: | 1999 |
| Předmět: |
Reoperation
medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Disease-Free Survival Breast cancer Breast-conserving surgery Humans Medicine Total Mastectomy Mastectomy business.industry Axillary Lymph Node Dissection medicine.disease Combined Modality Therapy Survival Analysis Surgery Radiation therapy Female Neoplasm Recurrence Local business Complication Quadrantectomy Follow-Up Studies |
| Zdroj: | British Journal of Surgery. 86:84-87 |
| ISSN: | 1365-2168 0007-1323 |
| DOI: | 10.1046/j.1365-2168.1999.00961.x |
| Popis: | Background This study aimed to analyse the possibility of surgical rescue of intrabreast tumour recurrence (IBTR) following conservative operation for breast cancer, i.e. quadrantectomy, axillary dissection and radiotherapy. Methods Of 2544 patients treated with this approach, 209 presented with an IBTR as the first and only sign of relapse. Some 197 patients were considered suitable for further surgery; 12 were inoperable. Six patients declined operation. Results Reoperative surgery was total mastectomy in 134 patients (70 per cent) and further local resection in 57 (30 per cent). Median follow-up after second surgery was 73 (range 1–192) months. The overall survival probability at 60 months was 70 per cent after mastectomy and 85 per cent following further local excision. There was no difference in disease-free survival between the two operative groups. Second IBTR was more common at 5 years in the re-excision group (19 versus 4 per cent). Conclusion Since the type of surgery did not seem to affect survival, breast conservation can be considered in selected patients with IBTR. |
| Databáze: | OpenAIRE |
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