Evaluation of cone biopsy in the management of carcinoma in situ of the cervix

Autor: Bradley Bigelow, E.Mark Beckman, Rita I. Demopoulos, Roger L. Garcia
Rok vydání: 1975
Předmět:
Zdroj: Gynecologic oncology. 3(1)
ISSN: 0090-8258
Popis: The success of conization in eradicating carcinoma in situ of the cervix was investigated. Between 1964 and 1973, 115 patients with carcinoma in situ of the cervix on cone biopsy were subsequently treated, within a maximum of 6 wk, by total hysterectomy. Residual significant disease (defined as carcinoma in situ or severe dysplasia) was found in the uterus of 51% of these patients. If in situ carcinoma was present at the surgical margins of resection in the cone biopsy, the incidence of residual significant disease in the uterus was 81%. Absence of in situ carcinoma at the surgical margin of the cone was associated with residual significant disease in the uterus in 31% of cases. This difference is statistically significant ( P
Databáze: OpenAIRE