Spontaneous bacterial peritonitis: update on diagnosis and treatment
| Autor: | Carmen Fierbințeanu-Braticevici, Roxana-Emanuela Popoiag |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Neutrophils Peritonitis 03 medical and health sciences 0302 clinical medicine Spontaneous bacterial peritonitis Internal medicine Ascites medicine Paracentesis Humans Effective treatment In patient multidrug-resistant organisms medicine.diagnostic_test business.industry cirrhosis Diagnostic marker Bacterial Infections Middle Aged medicine.disease RC31-1245 Anti-Bacterial Agents paracentesis spontaneous bacterial peritonitis Treatment Outcome 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology medicine.symptom Complication business |
| Zdroj: | Romanian Journal of Internal Medicine, Vol 59, Iss 4, Pp 345-350 (2021) |
| ISSN: | 2501-062X |
| DOI: | 10.2478/rjim-2021-0024 |
| Popis: | Spontaneous bacterial peritonitis (SBP) is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed in all patients with ascites and clinical features with high diagnostic suspicion. Although literature data abound in identifying new diagnostic markers in serum or ascites, they have not yet been validated. The final diagnosis requires the analysis of ascites and the presence of > 250 mm3 neutrophil polymorphonuclear (PMN) in ascites. If previous data showed that the most common microorganisms identified were represented by gram-negative bacteria, we are currently facing an increase in gram-positive bacteria and multidrug-resistant bacteria. Although prompt and effective treatment is required to prevent outcomes, this becomes challenging as first-line therapies may become ineffective leading to worsening prognosis and increased in-hospital mortality. In this paper we will make a brief review of existing data on the diagnosis and treatment of SBP. |
| Databáze: | OpenAIRE |
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