| Autor: |
Amanda Scheuermann, Amy Moskop, Amanda Hopp, Kathleen Bone, Holli M. Drendel, Julie Talano, Paul Harker-Murray, John Astle |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Journal of Pediatric Hematology/Oncology. 44:268-270 |
| ISSN: |
1077-4114 |
| DOI: |
10.1097/mph.0000000000002437 |
| Popis: |
Donor cell leukemia is a rare complication following hematopoietic stem cell transplant (HSCT). There are currently few reports in children and only rare, reported cases of donor-derived myelodysplastic syndrome/acute myeloid leukemia in patients with an underlying germline GATA2 mutation. Most reported cases are myeloid in origin and occur following related HSCT. We present a 3-year-old female who developed a donor-derived B-cell acute lymphoblastic leukemia 2 years post unrelated HSCT for GATA2 germline mutation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
