A school-based approach to the control of urinary schistosomiasis and intestinal helminth infections in children in Matuga, Kenya: impact of a two-year chemotherapy programme on prevalence and intensity of infections
| Autor: | Pascal Magnussen, Malick Ndzovu, Saidi Tosha, Peter Mungai, John H. Ouma, Eric M. Muchiri |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Veterinary medicine Trichuris Adolescent education Population Helminthiasis Schistosomiasis Albendazole Praziquantel Antiplatyhelmintic Agents Feces Hookworm Infections Schistosomiasis haematobia Internal medicine parasitic diseases medicine Prevalence Infection control Humans Trichuriasis Child Parasite Egg Count Anthelmintics education.field_of_study Ascariasis Schools biology business.industry Ascaris Antinematodal Agents Public Health Environmental and Occupational Health biology.organism_classification medicine.disease Kenya Infectious Diseases Levamisole Child Preschool Communicable Disease Control Parasitology Female business Public Health Administration medicine.drug |
| Zdroj: | Tropical medicineinternational health : TMIH. 2(9) |
| ISSN: | 1360-2276 |
| Popis: | A school- and chemotherapy-based urinary schistosomiasis and intestinal helminth infection control programme was conducted in Matuga Division, Kwale District, Coast Province with teachers taking care of diagnosis, treatment and health education. More than 12,000 children in 36 primary schools were included in the 2-year programme. Results for 20 evaluation schools are presented. Children with haematuria were treated with praziquantel (40 mg/kg) once a year. Within 2 years, the prevalence of haematuria in the schools was reduced from 28% (range 8-68%) to 11.4% (range 3-23%). More than 80% of the schoolchildren were infected with one or more intestinal helminths at baseline. After one year with levamisole mass chemotherapy, single dose (2.5 mg/kg) three times a year (once per school term), the prevalence of Ascaris infection was reduced by 83% from 18% to 3%, but there was no change in pretreatment prevalences of hookworm (57%) and Trichuris (56%) infections. In the second year of the programme, albendazole 600 mg once every six months was administered to the children in 10 randomly selected schools. This resulted in 52% and 23% reductions in prevalences of hookworm and Trichuris infections, respectively, in these schools and a reduction in mean intensity of infection of 52.8% and 50.3%, respectively. |
| Databáze: | OpenAIRE |
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