Evidence for naturally occurring recombination in the gene encoding the major outer membrane protein of lymphogranuloma venereum isolates of Chlamydia trachomatis

Autor: R A Ballard, G H Fehler, L J Hayes, Michael E. Ward, J D Treharne, P Yearsley
Rok vydání: 1994
Předmět:
Zdroj: Infection and Immunity. 62:5659-5663
ISSN: 1098-5522
0019-9567
DOI: 10.1128/iai.62.12.5659-5663.1994
Popis: The nucleotide sequence of the major outer membrane protein gene (omp1) was determined for three geographically distinct lymphogranuloma venereum isolates which were serologically untypeable. The three omp1 sequences were hybrids of serovars L1 and L2, containing a putative DNA recombination site in variable segment 2. Efforts to manipulate the chlamydial genome in vitro by recombination should be intensified.
Databáze: OpenAIRE