Isolated pancreatic metastasis from malignant melanoma: a case report and literature review

Autor: Reiko Yamada, Kazuhiko Kobayashi, Yu Fujimura, Hiroaki Naota, Maki Kaneko, Yoshifumi Nakamura, Masami Tabata, Kyosuke Tanaka
Jazyk: angličtina
Rok vydání: 2019
Předmět:
medicine.medical_specialty
Skin Neoplasms
Nose Neoplasms
Case Report
Multimodal Imaging
Endosonography
03 medical and health sciences
0302 clinical medicine
Fatal Outcome
Surgical oncology
Internal medicine
Positron Emission Tomography Computed Tomography
Biopsy
medicine
Pancreatic mass
Humans
Endoscopic retrograde cholangiopancreatogram (ERCP)
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Melanoma
Aged
Fluorodeoxyglucose
Cholangiopancreatography
Endoscopic Retrograde
medicine.diagnostic_test
Malignant melanoma
business.industry
Endoscopic ultrasound (EUS)
Gastroenterology
Magnetic resonance imaging
General Medicine
Hepatology
medicine.disease
Magnetic Resonance Imaging
Pancreatic Neoplasms
medicine.anatomical_structure
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Radiology
Pancreas
business
Tomography
X-Ray Computed
medicine.drug
Zdroj: Clinical Journal of Gastroenterology
ISSN: 1865-7265
1865-7257
Popis: Isolated pancreatic metastasis from malignant melanoma is rare. Pancreatic metastasis is difficult to diagnose in patients with unknown primary malignant melanoma. Endoscopic ultrasound-guided fine-needle aspiration plays an important role in confirming the diagnosis. A 67-year-old woman was referred to our institution because of a mass in her pancreas. Computed tomography and magnetic resonance imaging revealed a 35-mm mass localized on the pancreatic tail, with low attenuation, surrounded by a high-attenuation rim. Endoscopic ultrasonography revealed a hypoechoic mass with central anechoic areas. Endoscopic ultrasound-guided fine-needle aspiration of the mass was performed, and the pathological diagnosis was malignant melanoma. Intense fluorodeoxyglucose uptake was observed in the pancreatic tail on positron emission tomography–computed tomography. No other malignant melanoma was found. Distal pancreatectomy was performed. Six months postoperatively, positron emission tomography–computed tomography revealed high uptake in the left nasal cavity, and biopsy revealed the mass to be a malignant melanoma, indicating that the primary site of the malignant melanoma was the left nasal cavity and that the pancreatic mass and peritoneal lesion were metastases. The patient had survived > 2 years after the distal pancreatectomy. Pancreatic resection of isolated pancreatic metastasis can possibly prolong survival; however, metastatic melanoma usually has poor prognosis.
Databáze: OpenAIRE
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