Isolated Lymphoma of the Anterior Visual Pathway Diagnosed by Optic Nerve Biopsy
Autor: | George Lantos, Joseph R. Zelefsky, Floyd A. Warren, Carolyn H Revercomb |
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Rok vydání: | 2008 |
Předmět: |
Male
Antimetabolites Antineoplastic Pathology medicine.medical_specialty Lymphoma B-Cell Antineoplastic Agents Hormonal genetic structures Anterior Visual Pathway Biopsy Leucovorin Vision Low Optic chiasm Diagnosis Differential Fatal Outcome Antigens Neoplasm immune system diseases hemic and lymphatic diseases Glioma Biomarkers Tumor medicine Humans Neoplasm Invasiveness Treatment Failure Aged medicine.diagnostic_test business.industry Optic Nerve Neoplasms Primary central nervous system lymphoma Optic Nerve Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging eye diseases Lymphoma Ophthalmology Methotrexate medicine.anatomical_structure Optic Chiasm Vitamin B Complex Disease Progression Optic nerve Prednisone Neurology (clinical) business |
Zdroj: | Journal of Neuro-Ophthalmology. 28:36-40 |
ISSN: | 1070-8022 |
DOI: | 10.1097/wno.0b013e318167448e |
Popis: | A 72-year-old previously healthy man developed rapidly progressive visual loss, and brain imaging showed features suggestive of a malignant glioma of the anterior visual pathway. Biopsy of one optic nerve yielded a diagnosis of lymphoma. There was no evidence of an extracranial non-Hodgkin lymphoma, so the conclusion was that this represented a primary central nervous system lymphoma (PCNSL). PCNSL isolated to the optic chiasm has been described only once in an immunocompetent patient. Our patient is unusual in that the lymphoma involved the optic nerve, chiasm, and tract in an immunocompetent patient. |
Databáze: | OpenAIRE |
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