Changes in severity, mortality, and virus genome among a Spanish cohort of patients hospitalized with SARS-CoV-2
| Autor: | Rocío Aznar-Gimeno, Angel Lanas, M. José Esquillor-Rodrigo, Rafael del-Hoyo-Alonso, M. Trinidad Serrano, J. Ramón Paño-Pardo, Gorka Labata-Lezaun, David Abadía-Gallego, Carlos Tellería-Orriols, Luis M. Esteban, Francisco Díez-Fuertes |
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| Přispěvatelé: | Instituto Tecnológico de Aragón, Instituto de Investigación Sanitaria Aragón |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate analysis Adolescent Science Genome Viral Severity of Illness Index Cohort Studies Young Adult Risk Factors Internal medicine Pandemic Severity of illness Humans Medicine Longitudinal Studies Young adult Child Pandemics Aged Retrospective Studies Aged 80 and over Multidisciplinary SARS-CoV-2 business.industry Mortality rate COVID-19 Infant Retrospective cohort study Middle Aged Hospitalization Intensive Care Units Spain Child Preschool Multivariate Analysis Cohort Female business Cohort study |
| Zdroj: | Repisalud Instituto de Salud Carlos III (ISCIII) Zaguán. Repositorio Digital de la Universidad de Zaragoza Consejo Superior de Investigaciones Científicas (CSIC) Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021) |
| Popis: | Comparing pandemic waves could aid in understanding the evolution of COVID-19. The objective of the present study was to compare the characteristics and outcomes of patients hospitalized for COVID-19 in different pandemic waves in terms of severity and mortality. We performed an observational retrospective cohort study of 5,220 patients hospitalized with SARS-CoV-2 infection from February to September 2020 in Aragon, Spain. We compared ICU admissions and 30-day mortality, clinical characteristics, and risk factors of the first and second waves of COVID-19. The SARS-CoV-2 genome was also analyzed in 236 samples. Patients in the first wave (n = 2,547) were older (median age 74 years [IQR 60-86] vs. 70 years [53-85]; p |
| Databáze: | OpenAIRE |
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