The Fate of Chronic Burn Wounds Suspected as Marjolin’s Ulcers
| Autor: | Sang Hyun Woo, Chi Young Bang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Leiomyosarcoma Chronic wound medicine.medical_specialty Skin Neoplasms Adolescent Pseudoepitheliomatous Hyperplasia Poison control Malignancy Malignant transformation Cicatrix Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Skin Ulcer medicine Humans Aged Retrospective Studies Burn scar Aged 80 and over business.industry Rehabilitation 030208 emergency & critical care medicine Middle Aged Prognosis medicine.disease Dermatology Latency stage Chronic Disease Emergency Medicine Female Surgery medicine.symptom Burns business |
| Zdroj: | Journal of Burn Care & Research. :1 |
| ISSN: | 1559-047X |
| Popis: | Marjolin's ulcer is the malignant transformation of chronic nonhealing ulcers that have developed in burn scars or in any other chronic wound. Development of this malignancy tends to be slow and insidious, but it becomes more aggressive when the Marjolin's ulcer breaks free of the scar. We reviewed 24 cases of patients who complained of chronic burn wounds suspected to be Marjolin's ulcers. Histologically, chronic ulcer and pseudoepitheliomatous hyperplasia were 21%, respectively, and malignancy, including squamous cell carcinoma and leiomyosarcoma, were 58%. The mean latency period was 31.6 ± 13.0 years, and the majority of lesions occurred in the extremities. Pseudoepitheliomatous hyperplasia in chronic burn wounds, which is difficult to distinguish from squamous cell carcinoma and considered as a transitional state to becoming a malignant tumor, should be treated as a malignancy. An aggressive excision and reconstruction with free tissue transfer or regional flap transposition should be adopted for adequate ablation and definitive coverage, rather than skin graft and regular surveillance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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