Radiofrequency ablation of the liver abutting stomach: In vivo comparison of gastric injury before and after intragastric saline administration in a porcine model
| Autor: | Hyo Keun Lim, Kwangseon Min, Dongil Choi, Jongmee Lee, Seung Hoon Kim, Yong Hwan Jeon |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Pathology Swine Radiofrequency ablation medicine.medical_treatment Sodium Chloride law.invention Muscular layer Hypothermia Induced law Animals Hepatectomy Medicine Radiology Nuclear Medicine and imaging Saline Thermal injury business.industry Stomach Burns Electric General Medicine Hypothermia Ablation Treatment Outcome medicine.anatomical_structure Catheter Ablation Female Histopathology medicine.symptom business Nuclear medicine |
| Zdroj: | European Journal of Radiology. 72:154-159 |
| ISSN: | 0720-048X |
| Popis: | Purpose To compare the in vivo gastric injury observed during radiofrequency (RF) ablation of the liver abutting the stomach before and after the intragastric administration of chilled saline. Materials and methods Twenty RF ablation zones were created in the livers of 10 pigs with a 1-cm-exposed active tip of an internally cooled electrode under ultrasound guidance for 10 min. Ten RF ablation zones were created before (non-saline group) and after (saline group) the intragastric administration of approximately 1000 mL of chilled saline, and 20 RF ablation zones were made in the posterior part of the left lobe abutting the stomach. The frequency and severity of the thermal injury observed in the stomach of the two groups were compared histologically. Results All the resected gastric specimens showed thermal injuries of varying degrees of severity. The largest diameter of the gastric injury was significantly smaller in the saline group (mean 1.5 cm; range 1.3–1.8 cm) than in the non-saline group (mean 2.1 cm; range 1.8–2.4 cm) ( p = 0.000). The saline group showed significantly less thermal injury to the muscular layer of the gastric wall by the histopathology ( p = 0.033). Conclusions The intragastric administration of chilled saline might be a useful technique for reducing the severity of gastric injury during RF ablation of the liver abutting the stomach. |
| Databáze: | OpenAIRE |
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