Genome‐wide association study of fleece traits in Inner Mongolia Cashmere goats
| Autor: | Z. X. Wang, G. Gong, Li Zhang, R. J. Wang, X. C. Yan, F. T. Zhang, Jin-Quan Li, Z. H. Liu, F. H. Wang, L. T. Zhang, Y. J. Zhang, R. Su, Y. H. Zhao, L. B. He, H. F. Liu, Z. Y. Wang, Qi Lv |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
fleece traits China Short Communication Short Communications Single-nucleotide polymorphism Genome-wide association study Biology Significant snps Inner mongolia Polymorphism Single Nucleotide 03 medical and health sciences Genetics Cashmere goat Animals Inner Mongolia Cashmere goats genome‐wide association study Gene ontology Goats 0402 animal and dairy science GoatSNP52K Beadchip 04 agricultural and veterinary sciences General Medicine 040201 dairy & animal science Breed 030104 developmental biology Gene Ontology Animal Science and Zoology Genomic selection Genome-Wide Association Study Hair |
| Zdroj: | Animal Genetics |
| ISSN: | 1365-2052 0268-9146 |
| Popis: | Summary Inner Mongolia Cashmere goat is a well‐known local cashmere goat breed in China. It is famous for excellent fleece quality and a significant advantage in cashmere yield compared to other cashmere goat breeds. In this study, a genome‐wide association study was used to investigate fiber length, fiber diameter, and cashmere yield of 192 Inner Mongolia Cashmere goats using the Illumina GoatSNP52K Beadchip panel. We discovered that four single nucleotide polymorphisms (SNPs) reached genome‐wide significance levels. These SNPs were located in some genes, e.g. FGF12, SEMA3D, EVPL, and SOX5, possibly related to fleece traits in Inner Mongolia Cashmere goat. Gene ontology enrichment analysis revealed that these genes were enriched in several biological pathways that were involved in hair follicle development in cashmere goats. In summary, the identified significant SNPs and genes provide useful information to explore genetic mechanisms underlying the variation in fleece traits and genomic selection of Chinese cashmere goat. |
| Databáze: | OpenAIRE |
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