Spontaneous Recovery of Reduced Cortical Central Benzodiazepine Receptor Binding Potential on I-123 Iomazenil SPECT in a Patient With Status Epilepticus
| Autor: | Kohei Chida, Hiroki Kuroda, Akira Ogawa, Kuniaki Ogasawara, Takaaki Beppu, Masakazu Kobayashi, Kenta Aso |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Flumazenil medicine.medical_specialty Remission Spontaneous Spontaneous recovery Status epilepticus Status Epilepticus Internal medicine Spect imaging Humans Medicine Radiology Nuclear Medicine and imaging Receptor Benzodiazepine receptor binding Cerebral Cortex Tomography Emission-Computed Single-Photon Iomazenil business.industry General Medicine Receptors GABA-A Endocrinology Anesthesia Cerebral hemisphere Female medicine.symptom business Perfusion |
| Zdroj: | Clinical Nuclear Medicine. 35:126-127 |
| ISSN: | 0363-9762 |
| Popis: | A reduction in cortical benzodiazepine receptor binding potential on late images of I-123 iomazenil SPECT indicates irreversible neural damage or loss. We present the case of a 26-year-old woman with status epilepticus in whom SPECT imaging using I-123 iomazenil and I-123 N-isopropyl-p-iodoamphetamine 7 and 9 days after the last seizure, respectively, demonstrated reduction in central benzodiazepine receptor binding potential with hyperperfusion in the affected cerebral hemisphere and crossed cerebellar hypoperfusion. However, 3 months later, repeat studies showed resolution of the reduction in cortical benzodiazepine receptor binding potential, resolution of hyperperfusion, and resolution of crossed cerebellar hypoperfusion. |
| Databáze: | OpenAIRE |
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