Absorbable Adams-DeWeese caval clip: an experimental study
| Autor: | I. Jeanty, Denis Pariente, Pierre Olivier Sarfati, Philippe Bonnichon, P. Santoni, T. Meatchi, L. Su Ming, S. Crougneau |
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| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Vena Cava Filters Polymers medicine.medical_treatment education Materials testing Dogs Laparotomy Materials Testing medicine Retroperitoneal space Animals D-Lactic Acid cardiovascular diseases Lactic Acid Retroperitoneal Space CLIPS computer.programming_language Vena cava filters business.industry General Medicine Equipment Design medicine.disease Surgery Pulmonary embolism surgical procedures operative medicine.anatomical_structure Evaluation Studies as Topic cardiovascular system Female Cardiology and Cardiovascular Medicine business computer circulatory and respiratory physiology Abdominal surgery |
| Zdroj: | Annals of vascular surgery. 10(6) |
| ISSN: | 0890-5096 |
| Popis: | Adams-DeWeese caval clips have been shown to be effective in preventing pulmonary embolism. However, the use of Teflon clips constitutes a permanent solution for this transient risk. We tested an absorbable caval clip made of currently available synthetic biodegradable polymers in five female beagle dogs. The polymer used was PLA 96 containing 96% L lactic acid and 4% D lactic acid. After placement through a laparotomy, clips were routinely inspected and samples of the material were collected at regular intervals between 3 and 19 months postoperatively. The characteristics of absorption of PLA 96 in the retroperitoneal space were the same as those previously described in the literature. The clip retained its shape, rigidity, and effectiveness for 7 months. Complete degradation of the clip took between 18 and 19 months. Absorption did not cause a major inflammatory reaction and had no thrombogenic effect. Given the small number of animals studied, these results must be considered preliminary. |
| Databáze: | OpenAIRE |
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