Revisiting Prostate Cancer Recurrence with PSMA PET: Atlas of Typical and Atypical Patterns of Spread
| Autor: | Rafael F. Nunes, Felipe de Galiza Barbosa, Giovanni Guido Cerri, José Flávio Gomes Marin, Marcelo Queiroz, Carlos Alberto Buchpiguel, Publio Viana |
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| Rok vydání: | 2019 |
| Předmět: |
Glutamate Carboxypeptidase II
Male Biochemical recurrence medicine.medical_specialty Disease Genitalia Male urologic and male genital diseases 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Positron Emission Tomography Computed Tomography Humans Medicine Radiology Nuclear Medicine and imaging Neoplasm Metastasis business.industry Prostate Prostatic Neoplasms Bone metastasis medicine.disease Pelvic lymph nodes Patient management Bone scanning Positron-Emission Tomography 030220 oncology & carcinogenesis Psma pet Antigens Surface Radiology Neoplasm Recurrence Local Tomography X-Ray Computed business |
| Zdroj: | RadioGraphics. 39:186-212 |
| ISSN: | 1527-1323 0271-5333 |
| Popis: | The introduction of prostate-specific membrane antigen (PSMA) in clinical practice has revolutionized evaluation of biochemical recurrence of prostate cancer after curative-intent treatment. The high expression of this glycoprotein in prostate cancer cells makes PSMA imaging superior to the current conventional staging methods, namely bone scanning and CT. The high capability of PSMA imaging for identifying very small previously undetected lesions has been widely demonstrated in the literature, leading to a rethinking of patient management by oncologists, urologists, and radiation oncologists. The typical and predictable patterns of spread in prostate cancer are still more prevalent, such as spread to pelvic lymph nodes and bone metastasis, but different patterns of disease spread are becoming more commonly recognized with higher reliability because PSMA imaging allows detection of more typical and atypical lesions than conventional imaging. Furthermore, it is important for the reading physician to recognize and understand the typical disease spread and the most prevalent atypical prostate cancer relapses, not only to heighten the relevancy of reports but also to improve imaging consultancy in multispecialty oncologic practice. ©RSNA, 2019. |
| Databáze: | OpenAIRE |
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