Enhanced teeth whitening by nanofluidic transport of hydrogen peroxide into enamel with electrokinetic flows
| Autor: | Stacey Lavender, Frederico Barbosa de Sousa, Hiong Yap Gan, Wei Wang, Chenhui Peng, Shira Pilch, Jongyoon Han, Sohyun Park, Sang J. Lee |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
02 engineering and technology Carbamide Peroxide 03 medical and health sciences chemistry.chemical_compound Electrokinetic phenomena 0302 clinical medicine stomatognathic system Nano Tooth Bleaching Humans Urea General Materials Science In patient Hydrogen peroxide Dental Enamel General Dentistry Tooth whitening Molecular diffusion Enamel paint Nanoporous 030206 dentistry Hydrogen Peroxide 021001 nanoscience & nanotechnology Peroxides stomatognathic diseases chemistry Mechanics of Materials visual_art visual_art.visual_art_medium 0210 nano-technology Biomedical engineering |
| Zdroj: | Dental materials : official publication of the Academy of Dental Materials. 35(11) |
| ISSN: | 1879-0097 |
| Popis: | Tooth whitening, a routine procedure in dentistry, is one of the examples of medical procedures that are limited by the challenge of delivering molecules into various types of nanoporous tissues. Current bleaching methods rely on simple diffusion of peroxides into enamel nano channels, therefore requires sufficient contact time with peroxides. In-office treatments often involve enamel etching or light activation which often results in patient sensitivity and potential soft tissue damage. Objective To demonstrate a robust method to transport hydrogen peroxide to greater depths into enamel nanopores through nanofluidic flows driven by electrokinetics, with the intention to increase efficacy while reducing treatment time. Methods Freshly extracted human teeth were subjected to electrokinetic flow treatment with hydrogen peroxide under different electric fields with varying operation times. Pre- and post-operative shade matching was done using a photospectrometer. Results It is demonstrated that the operation time for the same concentration of hydrogen peroxide can be shortened by 10 times. The proposed method showed significant improvements in whitening effects over control groups and thus offers promising clinically-viable chairside applications with efficacy. Significance The demonstrated nanofluidic transport of hydrogen peroxide into enamel has a potential to be applied for enhancing tooth whitening, compared to simple diffusion, without heating the hard dental tissues. |
| Databáze: | OpenAIRE |
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