Daily life activities in patients with Alzheimer’s disease or semantic dementia: Multitasking assessment
| Autor: | Olivier Moreaud, Frédérique Etcharry-Bouyx, Catherine Merck, Serge Belliard, Josselin Baumard, Bernard Croisile, Clémence Coiffard, Charlène Lucas, Valérie Chauviré, Christophe Jarry, Didier Le Gall, François Osiurak, Mathieu Lesourd |
|---|---|
| Přispěvatelé: | Laboratoire de Psychologie des Pays de la Loire (LPPL), Université d'Angers (UA)-Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN), Laboratoire de Psychologie et NeuroCognition (LPNC ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre Hospitalier Universitaire [Grenoble] (CHU), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Memory Episodic Cognitive Neuroscience Semantic dementia Experimental and Cognitive Psychology Neuropsychological Tests Audiology 050105 experimental psychology 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Alzheimer Disease medicine Humans Semantic memory Human multitasking 0501 psychology and cognitive sciences Neuropsychological assessment Episodic memory ComputingMilieux_MISCELLANEOUS Memory Disorders medicine.diagnostic_test [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior 05 social sciences Neuropsychology Cognition medicine.disease Executive functions Frontotemporal Dementia Psychology 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychologia Neuropsychologia, Elsevier, 2021, 150, pp.107714. ⟨10.1016/j.neuropsychologia.2020.107714⟩ |
| ISSN: | 0028-3932 1873-3514 |
| DOI: | 10.1016/j.neuropsychologia.2020.107714⟩ |
| Popis: | The aim of the present study was to compare patients with mild to moderate Alzheimer's disease (AD) or semantic dementia (SD) on their cognitive processes and the severity of their daily life activity impairments. Three types of tasks were administered to patients (SD = 15; AD = 31) and 30 healthy controls (HC): 1) informant-based scales and questionnaires, 2) a neuropsychological assessment exploring executive functions, episodic and semantic memory, and 3) a new original test featuring multi-step naturalistic actions and multitasking: the Sequential Daily Life Multitasking (SDLM). We predicted that patients with AD would mainly exhibit task perplexity, associated with episodic and executive deficits on the SDLM, while the behavior of patients with SD would mostly be characterized by object perplexity, associated with semantic memory deficits. Results showed that patients with AD or SD were impaired across all neuropsychological tests, particularly episodic memory in AD and semantic memory in SD. General performance on the SDLM also appeared dramatically impaired in both patient groups, and correlated with results of questionnaires about instrumental activities and memory impairments. However, specific qualitative measurements on the SDLM did not allow us to pinpoint different patterns of errors and behavior in patients with AD versus SD. We suggest that the inability of patients in both groups to perform the SDLM may derive from a constellation of disorders or else from more subtle impairment of cognitive and conative processes that requires further exploration. |
| Databáze: | OpenAIRE |
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