Electroencephalographic correlates of periventricular white matter lesions in probable Alzheimer's disease
| Autor: | Charles A. Jungreis, Oscar L. Lopez, Richard P. Brenner, Steven T. DeKosky, James T. Becker, Donald Rezek |
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| Rok vydání: | 1995 |
| Předmět: |
Male
Pathology medicine.medical_specialty Cognitive Neuroscience Electroencephalography Cerebral Ventricles White matter Central nervous system disease Degenerative disease Alzheimer Disease medicine Dementia Humans Cerebral Ventriculography Aged Aged 80 and over medicine.diagnostic_test Middle Aged medicine.disease Magnetic Resonance Imaging Hyperintensity Psychiatry and Mental health medicine.anatomical_structure Periventricular white matter lesions Female Geriatrics and Gerontology Alzheimer's disease Psychology Tomography X-Ray Computed |
| Zdroj: | Europe PubMed Central |
| ISSN: | 1013-7424 |
| Popis: | We evaluated the relationship between periventricular white matter lesions (PWMLs) and EEG abnormalities in probable Alzheimer''s disease (AD). We visually analyzed the EEG of 27 probable AD patients with mild to moderate degree of cognitive impairment participating in a longitudinal study of dementia. Patients had both CT and MRI scans performed at baseline examination, which also included an EEG. PWMLs were rated in CT and MRI films using a semiquantitative method. The EEGs were classified according to the Mayo Clinic Classification System. Abnormal EEGs correlated with PWMLs rating scores were detected on CT, but not on MRI. These data suggest that the presence of PWMLs contribute to the abnormal EEGs observed in AD patients, and that white matter abnormalities in CT correlate better with both the clinical findings and EEG than does the more sensitive but less specific MRI. |
| Databáze: | OpenAIRE |
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