Sensorimotor, Attentional, and Neuroanatomical Predictors of Upper Limb Motor Deficits and Rehabilitation Outcome after Stroke
| Autor: | Michele De Filippo De Grazia, Lorenza Maistrello, Francesca Meneghello, Marco Zorzi, Daniela D'Imperio, Eugenia Durgoni, Camilla Della Pietà, Zaira Romeo, Andrea Turolla |
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| Přispěvatelé: | D'Imperio D., Romeo Z., Maistrello L., Durgoni E., Pieta C.D., De Grazia M.D.F., Meneghello F., Turolla A., Zorzi M. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Article Subject medicine.medical_treatment Neurosciences. Biological psychiatry. Neuropsychiatry Corpus callosum Lateralization of brain function Functional Laterality Upper Extremity Physical medicine and rehabilitation Cognition Retrospective Studie Parietal Lobe medicine Movement Disorder Humans Stroke Aged Retrospective Studies Aged 80 and over Rehabilitation Movement Disorders business.industry Superior longitudinal fasciculus Stroke Rehabilitation Recovery of Function Middle Aged medicine.disease Magnetic Resonance Imaging Frontal Lobe medicine.anatomical_structure Treatment Outcome Neurology Corticospinal tract Female Neurology (clinical) business Insula Psychomotor Performance Human Research Article RC321-571 |
| Zdroj: | Neural Plasticity, Vol 2021 (2021) Neural Plasticity |
| ISSN: | 2090-5904 |
| DOI: | 10.1155/2021/8845685 |
| Popis: | The rehabilitation of motor deficits following stroke relies on both sensorimotor and cognitive abilities, thereby involving large-scale brain networks. However, few studies have investigated the integration between motor and cognitive domains, as well as its neuroanatomical basis. In this retrospective study, upper limb motor responsiveness to technology-based rehabilitation was examined in a sample of 29 stroke patients (18 with right and 11 with left brain damage). Pretreatment sensorimotor and attentional abilities were found to influence motor recovery. Training responsiveness increased as a function of the severity of motor deficits, whereas spared attentional abilities, especially visuospatial attention, supported motor improvements. Neuroanatomical analysis of structural lesions and white matter disconnections showed that the poststroke motor performance was associated with putamen, insula, corticospinal tract, and frontoparietal connectivity. Motor rehabilitation outcome was mainly associated with the superior longitudinal fasciculus and partial involvement of the corpus callosum. The latter findings support the hypothesis that motor recovery engages large-scale brain networks that involve cognitive abilities and provides insight into stroke rehabilitation strategies. |
| Databáze: | OpenAIRE |
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