Periodontal regeneration following application of basic fibroblast growth factor-2 in combination with beta tricalcium phosphate in class III furcation defects in dogs

Autor:	Toshinori Nakajima, Tomomi Takahashi, Mariko Kimura, Emiko Saito, Yoshinori Kuboki, Noboru Ohata, Tsuyoshi Kato, Fumihiko Yuge, Yoshiyuki Honma, Akira Saito
Rok vydání:	2013
Předmět:	Calcium Phosphates Materials science Periodontal Ligament Tooth Ankylosis Basic fibroblast growth factor Acid Phosphatase Root Resorption Dentistry Connective tissue Biocompatible Materials Class iii Cementum Formation Epithelium Root Planing chemistry.chemical_compound Random Allocation Dogs Beta-tricalcium phosphate Osteogenesis medicine Animals Regeneration Bicuspid Cementogenesis Fibroblast General Dentistry business.industry Tartrate-Resistant Acid Phosphatase Regeneration (biology) Furcation Defects Furcation defect Isoenzymes medicine.anatomical_structure chemistry Connective Tissue Bone Substitutes cardiovascular system Ceramics and Composites Guided Tissue Regeneration Periodontal Female Fibroblast Growth Factor 2 Collagen business Biomarkers
Zdroj:	Dental materials journal. 32(2)
ISSN:	1881-1361
Popis:	The aim of this study was to investigate the effect of tunnel structured β-tricalcium phosphate (β-TCP) on the regenerative potential of basic fibroblast growth factor-2 (bFGF-2) in class III furcation defects in dogs. The furcations of 30 mandibular premolar teeth received: 1) 0.3% bFGF-2 solution in conjunction with β-TCP; 2) 0.3% bFGF-2 solution; and 3) no implant material (Control group). The dogs were sacrificed 8 weeks post-surgery, and healing was evaluated histologically. New bone formation was significantly greater in the bFGF-2/β-TCP group compared to the bFGF-2 solution and Control groups (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d240eba882700e3f62ef00686e7e7ee2 https://pubmed.ncbi.nlm.nih.gov/23538761 Zobrazit plný text záznamu