Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives

Autor: Rahul Bhome, Mohamad Hussain, Owen Thorpe, Conor Keogh, Muhamed Farhan-Alanie, DEVENDER MITTAPALLI, Aditya Borakati, Christopher Graham, Vinci Naruka, Moritz Schramm, Prasanna Partha Sarathy, Kritchai Vutipongsatorn, Souradip Mookerjee, James Fitzgerald, Matthew Hague, Shaikh Sanjid Seraj, Emily Greenan, Samira Bell, Abdul Badran, Hannah Charlotte Copley, Clementina Calabria, Bradley Storey, Abdul-Rahman Gomaa, Dimitrios Karponis, Fraser Peck, Wen Jie Koay, Shyam Gokani, Thomas Pinkney, Luke McMenamin, Liam Cato, Sameera A, Eve Robertson, Edward Balai, Timothy Shao Ern Tan, Jonathan Lund, Peter Coe, Stephen Robinson, STARSurg Collaborative, Joshua Burke, Melika Akhbari, James Glasbey, Jonathan Bannard-Smith, Catrin Morgan, Ewen Harrison, Paul Glen, Claire Donohoe, Heather Davis, Richard Bogle, Tom Abbott, Emily Mills, Mehnoor Khaliq, Alex Elizabeth Ward, Sivesh K Kamarajah, Joanna Osmanska, Stefano Capella, Stephen O'Neill, Harry VM Spiers, Scott Smith, Kenneth A McLean, SOO KUN LIM, Thomas Ashdown, John Hayes, Gargi Samarth, Dalvir Bajwa, John Hardie, Adnan Ali, Emanuele Gammeri, Roudi Bachar, Jaspreet Kaur Seehra, Chung Shen Chean
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Medical Research Methodology
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-7 (2019)
Bannard-Smith, J 2019, ' Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives. ', BMC Medical Research Methodology . https://doi.org/10.1186/s12874-019-0857-y
ISSN: 1471-2288
Popis: Background Trainee research collaboratives (TRCs) have pioneered high quality, prospective ‘snap-shot’ surgical cohort studies in the UK. Outcomes After Kidney injury in Surgery (OAKS) was the first TRC cohort study to attempt to collect one-year follow-up data. The aims of this study were to evaluate one-year follow-up and data completion rates, and to identify factors associated with improved follow-up rates. Methods In this multicentre study, patients undergoing major gastrointestinal surgery were prospectively identified and followed up at one-year following surgery for six clinical outcomes. The primary outcome for this report was the follow-up rate for mortality at 1 year. The secondary outcome was the data completeness rate in those patients who were followed-up. An electronic survey was disseminated to investigators to identify strategies associated with improved follow-up. Results Of the 173 centres that collected baseline data, 126 centres registered to participate in one-year follow-up. Overall 62.3% (3482/5585) of patients were followed-up at 1 year; in centres registered to collect one-year outcomes, the follow-up rate was 82.6% (3482/4213). There were no differences in sex, comorbidity, operative urgency, or 7-day postoperative AKI rate between patients who were lost to follow-up and those who were successfully followed-up. In centres registered to collect one-year follow-up outcomes, overall data completeness was 83.1%, with 57.9% (73/126) of centres having ≥95% data completeness. Factors associated with increased likelihood of achieving ≥95% data completeness were total number of patients to be followed-up (77.4% in centres with 60 patients, p = 0.030), and central versus local storage of patient identifiers (72.5% vs 48.0%, respectively, p = 0.006). Conclusions TRC methodology can be used to follow-up patients identified in prospective cohort studies at one-year. Follow-up rates are maximized by central storage of patient identifiers.
Databáze: OpenAIRE
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