Demystified ... Human endogenous retroviruses
| Autor: | P R Carnegie, H Davari Ejtehadi, Paul Hooley, Paul N. Nelson, P Warren, J Martin, Sarah Rowland-Jones, Denise A. Roden, J Astley, Paul Murray |
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| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Genes
Viral Transcription Genetic viruses Endogenous retrovirus Reviews Biology medicine.disease_cause Antibodies Viral Genome Pathology and Forensic Medicine Autoimmune Diseases DNA Transposable Elements Neoplasms Drug Resistance Viral medicine Humans RNA Messenger Antigens Viral Genetics Human endogenous retrovirus Genome Human Terminal Repeat Sequence Endogenous Retroviruses Terminal Repeat Sequences DNA Codon Nonsense embryonic structures Intercellular Signaling Peptides and Proteins Human genome Carcinogenesis Peptides |
| Zdroj: | JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY. 56(1) |
| ISSN: | 1366-8714 |
| Popis: | Human endogenous retroviruses (HERVs) are a family of viruses within our genome with similarities to present day exogenous retroviruses. HERVs have been inherited by successive generations and it is possible that some have conferred biological benefits. However, several HERVs have been implicated in certain cancers and autoimmune diseases. This article demystifies these retroviruses by providing an insight into HERVs, their means of classification, and a synopsis of HERVs implicated in cancer and autoimmunity. Furthermore, the biological roles of HERVs are explored. |
| Databáze: | OpenAIRE |
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