Intravenous anaesthetics: some cellular sites of action
Autor: | Adrian W. Gelb, M Dzoljic |
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Rok vydání: | 1997 |
Předmět: |
business.industry
Central nervous system Long-term potentiation Inhibitory neurotransmitter Pharmacology Ion Channels Receptors Adrenergic Butyric acid chemistry.chemical_compound Anesthesiology and Pain Medicine medicine.anatomical_structure chemistry Receptors GABA Receptors Glutamate Anesthetics Inhalation Excitatory postsynaptic potential Medicine Animals Humans Ketamine business Receptor Anesthetics Intravenous medicine.drug |
Zdroj: | European journal of anaesthesiology. Supplement. 15 |
ISSN: | 0952-1941 |
Popis: | Intravenous anaesthetics have diverse effects on neurones within the central nervous system. Only those that occur at clinical concentrations are likely to be relevant. The dominant effect of many agents is the potentiation of the inhibitory neurotransmitter gamma amino butyric acid (GABA) by various mechanisms while inhibiting the effects of excitatory transmitters seems to be less dominant, except for ketamine. |
Databáze: | OpenAIRE |
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