Computer-aided detection of colorectal polyps: can it improve sensitivity of less-experienced readers? Preliminary findings
| Autor: | Luca Bogoni, Sarang Lakare, Michael Macari, Dina F. Caroline, Andrew Blum, Anna Jerebko, Mark E. Baker, Erick M. Remer, Chandra Dass, Renee M. Kendzierski, David M. Einstein, Pascal Cathier, Nancy A. Obuchowski |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Virtual colonoscopy medicine.diagnostic_test business.industry Colonoscopy Colonic Polyps Intestinal Polyps Software package Sensitivity and Specificity Computer aided detection Computed tomographic Rectal Diseases Informed consent medicine Feasibility Studies Humans Radiology Nuclear Medicine and imaging False Positive Reactions Radiology Clinical Competence Diagnosis Computer-Assisted Clinical competence business Reference standards Colonography Computed Tomographic |
| Zdroj: | Radiology. 245(1) |
| ISSN: | 0033-8419 |
| Popis: | To determine whether computer-aided detection (CAD) applied to computed tomographic (CT) colonography can help improve sensitivity of polyp detection by less-experienced radiologist readers, with colonoscopy or consensus used as the reference standard.The release of the CT colonographic studies was approved by the individual institutional review boards of each institution. Institutions from the United States were HIPAA compliant. Written informed consent was waived at all institutions. The CT colonographic studies in 30 patients from six institutions were collected; 24 images depicted at least one confirmed polyp 6 mm or larger (39 total polyps) and six depicted no polyps. By using an investigational software package, seven less-experienced readers from two institutions evaluated the CT colonographic images and marked or scored polyps by using a five-point scale before and after CAD. The time needed to interpret the CT colonographic findings without CAD and then to re-evaluate them with CAD was recorded. For each reader, the McNemar test, adjusted for clustered data, was used to compare sensitivities for readers without and with CAD; a Wilcoxon signed-rank test was used to analyze the number of false-positive results per patient.The average sensitivity of the seven readers for polyp detection was significantly improved with CAD-from 0.810 to 0.908 (P=.0152). The number of false-positive results per patient without and with CAD increased from 0.70 to 0.96 (95% confidence interval for the increase: -0.39, 0.91). The mean total time for the readings was 17 minutes 54 seconds; for interpretation of CT colonographic findings alone, the mean time was 14 minutes 16 seconds; and for review of CAD findings, the mean time was 3 minutes 38 seconds.Results of this feasibility study suggest that CAD for CT colonography significantly improves per-polyp detection for less-experienced readers. |
| Databáze: | OpenAIRE |
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