Tissue reaction to novel customized calcium silicate cement based dental implants. A pilot study in the dog
| Autor: | Steven M. Morgano, Andrew Sullivan, Mohammad Ali Saghiri, Amir Fakhrzadeh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Materials science Biocompatibility Periodontal Ligament medicine.medical_treatment Radiography Biomedical Engineering Biophysics Dentistry Bioengineering Pilot Projects Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dogs Imaging Three-Dimensional Osseointegration medicine Dentin Periodontal fiber Animals Tooth Socket Dental implant 030304 developmental biology Dental Implants Inflammation 0303 health sciences business.industry Silicates 030206 dentistry X-Ray Microtomography Calcium Compounds Biomechanical Phenomena Polyvinyl siloxane medicine.anatomical_structure chemistry Calcium silicate Tooth Extraction Implant business Biocompatibility Studies Silicate Cement |
| Zdroj: | Journal of Materials Science. Materials in Medicine |
| ISSN: | 1573-4838 0957-4530 |
| Popis: | Objectives The purpose of this study was to determine the level of periodontal tissue regeneration in a canine model following post-extraction placement of an implant molded from a composite material made from extracted tooth dentin and a calcium silicate cement (CSC) material. The investigation used autologous dentin in conjunction with a CSC material to form a composite implant designed for immediate tooth replacement. Methods Two (2) beagles had a periodontal and radiographic examination performed to rule out any pre-treatment inflammation, significant periodontal disease, or mobility. Then, ination eleven (11) teeth were extracted and polyvinyl siloxane molds were made to fabricate three different types of implants: Particulate Implant (Test Group 1, n = 4), Shell Implant Alone (Test Group 2, n = 2), Shell Implant with Emdogain® (Test Group 3, n = 3). Teeth in the control group were extracted, scaled (n = 2), and then re-implanted into their respective fresh extraction sockets. At 4 weeks, a clinical, radiographic, and histologic assessment was performed. Results Clinical evaluation revealed no mobility in any of the test or control implants and no radiographic evidence of significant bone loss or active disease. Based on the MicroCT analysis, direct bone to implant contact was observed in some areas with an apparent periodontal ligament space. Implant-related inflammation, on average, was similar among all groups, with low numbers of infiltrates. Implant-related inflammatory reaction was generally minimal and not interpreted to be adverse. Conclusion The proposed novel composite materials revealed that not only do these materials demonstrate high biocompatibility, but also their successful integration in the alveolus is likely secondary to a partial ligamentous attachment. The current investigation may lead to the use of calcium silicate-based materials as custom dental implants. Further research on this novel composite’s biomechanical properties is necessary to develop the optimal material composition for use as a load-bearing dental implant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink