Prevalence of HIV infection among people with disabilities: a population-based observational study in Yaoundé, Cameroon (HandiVIH)

Autor: Estelle Pasquier, Daniel Mont, Adonis Touko, Arne Henning Eide, Alice Tchoumkeu, Gervais Beninguisse, Frida Essomba, Aude Brus, Toyin Janet Aderemi, Jill Hanass-Hancock, Muriel Mac-Seing, Pierre De Beaudrap
Přispěvatelé: DeBeaudrap, Pierre, Département Sociétés et Mondialisation - SOC (Axe 3 - Éducation et Savoirs au Sud), Centre population et développement (CEPED - UMR_D 196), Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut de formation et de recherche démographiques (IFORD), Initiative 5% (Sida, Tuberculose, Paludisme), Expertise France [Paris]-Le Fonds mondial de Lutte contre le Sida, la Tuberculose et le Paludisme, Forum Camerounais de Psychologie (FOCAP), Etudes techniques et Recherche scientifique [Lyon], Handicap International France [Lyon], Ayahulet Consulting, Medical Research Council [South African], University of KwaZulu-Natal [Durban, Afrique du Sud] (UKZN), Stiftelsen for INdustriell og TEknisk Forskning Digital [Trondheim] (SINTEF Digital), School of Public Health [Montréal], Université de Montréal (UdeM), Leonard Cheshire Disability & Inclusive Development Centre [London, UK], University College de Londres [U.K.] (UCL - U.K.), This study was funded by the Agence national de recherches sur le sida et les hépatites virales (ANRS-Inserm) and the 5% Initiative., Institut de Recherche pour le Développement (IRD [France-Sud])-Centre population et développement (CEPED - UMR_D 196), Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5)-Institut de Recherche pour le Développement (IRD)-Université Paris Descartes - Paris 5 (UPD5), University of KwaZulu-Natal (UKZN), Département Sociétés et Mondialisation - SOC ( Axe 3 - Éducation et Savoirs au Sud ), Centre population et développement ( CEPED - UMR_D 196 ), Institut de Recherche pour le Développement ( IRD ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut de Recherche pour le Développement ( IRD ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut de Recherche pour le Développement ( IRD [France-Sud] ), Institut de formation et de recherche démographiques ( IFORD ), Institut de formation et de recherche démographiques, Initiative 5% ( Sida, Tuberculose, Paludisme ), Forum Camerounais de Psychologie ( FOCAP ), University of KwaZulu-Natal ( UKZN ), The Foundation for Scientific and Industrial Research ( SINTEF ), Université de Montréal ( UdeM ), University College de Londres [U.K.] ( UCL - U.K. )
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Adult
Male
Gerontology
030506 rehabilitation
Adolescent
Epidemiology
Cross-sectional study
Sexual Behavior
Immunology
Population
HIV Infections
Vulnerable Populations
Population control
Young Adult
03 medical and health sciences
0302 clinical medicine
5. Gender equality
Risk Factors
Virology
Prevalence
Humans
Medicine
Disabled Persons
Cameroon
030212 general & internal medicine
Young adult
10. No inequality
education
Sex work
education.field_of_study
Sexual violence
business.industry
1. No poverty
[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie
Odds ratio
Middle Aged
3. Good health
Cross-Sectional Studies
Infectious Diseases
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
Health Resources
Female
Observational study
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
0305 other medical science
business
Zdroj: Lancet HIV
Lancet HIV, 2017, [Epub ahead of print]. ⟨10.1016/S2352-3018(16)30209-0⟩
Lancet HIV, Elsevier, 2017, [Epub ahead of print]. ⟨10.1016/S2352-3018(16)30209-0⟩
Lancet HIV, Elsevier, 2017, [Epub ahead of print]. 〈10.1016/S2352-3018(16)30209-0〉
ISSN: 2405-4704
2352-3018
DOI: 10.1016/S2352-3018(16)30209-0
Popis: Summary Background In resource-limited settings, people with disabilities have been left behind in the response to HIV. In the HandiVIH study, we estimate and compare HIV prevalence and associated risk factors between people with and without disabilities. Methods In this cross-sectional, population-based, observational study, we used two-phase random sampling to recruit adults with disabilities and a control group matched for age, sex, and residential location from households of the general population. We used the Washington Group Short Set of Questions on Disability to identify people with disabilities. We administered an HIV test and a life-course history interview to participants. The primary outcome was the prevalence of HIV among participants with and without disabilities. Findings Between Oct 2, 2014, and Nov 30, 2015, we recruited 807 people with disabilities and 807 participants without disabilities from Yaounde, Cameroon. 28 of 716 people in the control population had a positive HIV test result (crude prevalence 3·9%, 95% CI 2·9–5·3) compared with 50 of 739 people with disabilities (6·8%, 5·0–8·6; conditional odds ratio [OR] 1·7; p=0·04). Women with disabilities were more often involved in paid sexual relationships than were women without disabilities (2·5% vs 0·5%, p=0·05). People with disabilities were also at increased risk of sexual violence than were women without disabilities (11·0% vs 7·5%, OR 1·5; p=0·01). Sexual violence and sex work were strongly associated with increased risk of HIV infection among participants with disabilities but not among controls (OR 3·0, 95% CI 1·6–5·6 for sexual violence and 12·3, 4·4–34·6 for sex work). Analyses were done in men and women. Interpretation The higher prevalence of HIV infection in people with disabilities than people without disabilities reflects a higher exposure to HIV infection as well as the presence of disability-associated HIV infection. The susceptibility of people with disabilities to HIV infection seems to be shaped by social and environmental factors. Research is needed to inform firm recommendations on how to protect this vulnerable population. Funding Agence nationale de recherches sur le sida et les hepatites virales (ANRS-Inserm) and the 5% Initiative.
Databáze: OpenAIRE
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