Tasks of activities of daily living (ADL) are more valuable than the classical neurological examination to assess upper extremity function and mobility in multiple sclerosis
| Autor: | Ludwig Kappos, Lorcan Walsh, Saskia Steinheimer, Jonas F. Dorn, Manuela Diederich, Marcus D’Souza, Caspar E. P. van Munster, Jessica Burggraaff, Frank Dahlke, Kristina Kravalis, Bernard M. J. Uitdehaag, Christian P. Kamm |
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| Přispěvatelé: | Neurology, Amsterdam Neuroscience - Neuroinfection & -inflammation |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Activities of daily living Motor dysfunction Multiple Sclerosis Neurological examination 610 Medicine & health Upper Extremity 03 medical and health sciences Disability Evaluation 0302 clinical medicine Physical medicine and rehabilitation Surveys and Questionnaires Activities of Daily Living upper extremity function Medicine Humans 030212 general & internal medicine Neurologic Examination medicine.diagnostic_test business.industry Multiple sclerosis ambulation Middle Aged medicine.disease mobility Neurology disability Arm Female Neurology (clinical) business Original Research Papers 030217 neurology & neurosurgery |
| Zdroj: | Multiple Sclerosis Journal, 25(12), 1673-1681. SAGE Publications Ltd van Munster, C. E.; D'Souza, M.; Steinheimer, Saskia Marie; Kamm, Christian Philipp; Burggraaff, J.; Diederich, M.; Kravalis, K.; Dorn, J.; Walsh, L.; Dahlke, F.; Kappos, L.; Uitdehaag, B. M. (2019). Tasks of activities of daily living (ADL) are more valuable than the classical neurological examination to assess upper extremity function and mobility in multiple sclerosis. Multiple sclerosis journal, 25(12), pp. 1673-1681. Sage 10.1177/1352458518796690 Multiple Sclerosis (Houndmills, Basingstoke, England) van Munster, C E P, D’Souza, M, Steinheimer, S, Kamm, C P, Burggraaff, J, Diederich, M, Kravalis, K, Dorn, J, Walsh, L, Dahlke, F, Kappos, L & Uitdehaag, B M J 2019, ' Tasks of activities of daily living (ADL) are more valuable than the classical neurological examination to assess upper extremity function and mobility in multiple sclerosis ', Multiple Sclerosis Journal, vol. 25, no. 12, pp. 1673-1681 . https://doi.org/10.1177/1352458518796690 |
| ISSN: | 1352-4585 |
| DOI: | 10.1177/1352458518796690 |
| Popis: | Background: Accurate clinical assessment in multiple sclerosis (MS) is challenging. The Assess MS system is being developed to automatically quantify motor dysfunction in MS, including upper extremity function (UEF) and mobility. Objective: To determine to what extent combinations of standardized movements included in the Assess MS system explain accepted measures of UEF and mobility. Methods: MS patients were recruited at four European MS centres. Eight movements were selected, including tasks of activities of daily living (ADL) and classical neurological tests. Movements were recorded on video and rated by experienced neurologists ( n = 5). Subsequently, multivariate linear regression models were performed to explain the variance of the Nine-Hole Peg Test (9HPT), Arm Function in Multiple Sclerosis Questionnaire (AMSQ) and Timed-25 Foot Walk test (T25WT). Results: In total, 257 patients were included. The movements explained 62.9% to 80.1% of the variance of the 9HPT models, 43.3% and 44.3% of the AMSQ models and 70.8% of the T25WT. In all models, tasks of ADL contributed most to the variance. Conclusion: Combinations of movements are valuable to assess UEF and mobility. Incorporating ADL tasks into daily clinical practice and clinical trials may be more valuable than the classical neurological examination of UEF and mobility. |
| Databáze: | OpenAIRE |
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