Photic stimulation-induced alteration of brain energy metabolism measured by 31P-MR spectroscopy in patients with MELAS
| Autor: | Toshiki Shioiri, Tadafumi Kato, Jun Murashita, Nobumasa Kato, Toshiro Inubushi, Masahiko Terada |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
medicine.medical_specialty Magnetic Resonance Spectroscopy Phosphocreatine genetic structures Photic Stimulation Encephalopathy Stimulation Biology MELAS syndrome Phosphates chemistry.chemical_compound Mitochondrial myopathy Internal medicine Cortex (anatomy) MELAS Syndrome medicine Humans Brain Phosphorus Isotopes Middle Aged medicine.disease Endocrinology medicine.anatomical_structure Neurology chemistry Lactic acidosis Female sense organs Neurology (clinical) Energy Metabolism |
| Zdroj: | Journal of the Neurological Sciences. 155:182-185 |
| ISSN: | 0022-510X |
| DOI: | 10.1016/s0022-510x(97)00308-0 |
| Popis: | We examined brain energy metabolism by phosphorus-31 magnetic resonance spectroscopy (31P-MRS) in the occipital cortex in a mother and a daughter with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) during photic stimulation. The peak area ratio of phosphocreatine markedly decreased during photic stimulation, and subsequently increased after the stimulation. This method, photic stimulation-31P-MRS, may be useful in assessing brain energy metabolism in neurological diseases. |
| Databáze: | OpenAIRE |
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