Prevalence of Transmitted HIV-1 Drug Resistance Mutations in Children and Adolescents in São Paulo, Brazil

Autor:	Flávia Jacqueline Almeida, Marco Aurélio Palazzi Sáfadi, André Minhoto Lança, Rosangela Rodrigues, Luís Fernando de Macedo Brígido, Mayra Simioni Zaparoli, João Leandro de Paula Ferreira, Eitan Naaman Berezin
Rok vydání:	2012
Předmět:	Male Microbiology (medical) Pediatrics medicine.medical_specialty Adolescent Genotype medicine.medical_treatment Population Mutation Missense HIV Infections Drug resistance Nucleoside Reverse Transcriptase Inhibitor Drug Resistance Viral medicine Prevalence Humans education Child education.field_of_study Protease Transmission (medicine) business.industry Infant Newborn Infant Virology Reverse transcriptase Infectious Diseases Child Preschool Pediatrics Perinatology and Child Health HIV-1 Female business HIV drug resistance Brazil
Zdroj:	The Pediatric Infectious Disease Journal. :1
ISSN:	0891-3668
Popis:	HIV drug resistance genotype testing, performed on 39 HIV-infected treatment-naive children from 2000 to 2011, identified 5 children (12.8%) with drug resistance mutations: 5.3% to nucleoside reverse transcriptase inhibitors, 5.3% to nonnucleoside reverse transcriptase inhibitors and 7.7% to protease inhibitors. There was a trend for increasing prevalence of drug resistance mutations during the 11-year study period.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d216f3adaebcdc99a9e8263c4ab2bfac https://doi.org/10.1097/inf.0b013e3182678c19 Zobrazit plný text záznamu