Successful treatment of pyoderma gangrenosum with concomitant immunoglobulin A nephropathy: A case report and review of literature
Autor: | Zhi-Gang Ma, Wen-Hui Huang, Xiaoli Li, Yunfei Hao, Er-Qing Chai |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Case Report Nephropathy 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Pyoderma gangrenosum Immunoglobulin A nephropathy Erythematous plaque medicine Hypoalbuminemia 030203 arthritis & rheumatology Proteinuria integumentary system business.industry General Medicine Abdominal distension medicine.disease Dermatology Treatment Cutaneous condition Prednisolone medicine.symptom business medicine.drug |
Zdroj: | World Journal of Clinical Cases |
ISSN: | 2307-8960 |
DOI: | 10.12998/wjcc.v6.i13.703 |
Popis: | Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous condition of an unknown etiology and is often associated with immune diseases. However, PG rarely shows visceral involvement, especially in the kidney. A 20-year-old female presented with pedal edema and skin ulceration of both lower limbs. The skin lesion began as an erythematous plaque and then became a blister. She also complained of abdominal distension and a decreasing urine volume. Laboratory data showed high proteinuria, hypoalbuminemia and hyperlipidemia. Her skin and kidney were biopsied. The pathological results indicated PG and immunoglobulin A (IgA) nephropathy. The patient was finally cured with prednisolone in combination with cyclosporine A (CsA). |
Databáze: | OpenAIRE |
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