Associations of Physical Activity Energy Expenditure with Nutritional-Inflammatory Markers in Hemodialysis Patients
| Autor: | Antonio Alberto Lopes, Cácia Mendes Matos, Fernanda A Silva, Maria Tereza Silveira Martins, Luciana F Silva, Gildete Barreto Lopes, Márcia Tereza Silva Martins, Angiolina Campos Kraychete, Marcelo Barreto Lopes, Clarcson Plácido Conceição dos Santos |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study medicine.medical_treatment 030232 urology & nephrology Biomedical Engineering Nutritional Status Medicine (miscellaneous) Bioengineering Inflammation Biomaterials 03 medical and health sciences 0302 clinical medicine Renal Dialysis Internal medicine Odds Ratio medicine Humans Prospective Studies 030212 general & internal medicine Prospective cohort study Exercise Dialysis business.industry General Medicine Odds ratio Middle Aged Prognosis medicine.disease Malnutrition C-Reactive Protein Cross-Sectional Studies Logistic Models Kidney Failure Chronic Female Hemodialysis medicine.symptom Energy Metabolism business Biomarkers Brazil Kidney disease |
| Zdroj: | The International Journal of Artificial Organs. 40:670-675 |
| ISSN: | 1724-6040 0391-3988 |
| Popis: | Background Sedentariness, high inflammation status and malnutrition are highly prevalent in end-stage kidney disease patients on maintenance hemodialysis (MHD). This study investigated associations of weekly physical activity energy expenditure (PAEE) with clinical and anthropometric markers of nutrition and inflammation. Methods The analysis was performed using baseline cross-sectional data of 640 patients enrolled in the prospective cohort “The Prospective Study of the Prognosis of Patients Treated Chronically by Hemodialysis” (PROHEMO) developed in Salvador, BA, Brazil. The long version of the International Physical Activity Questionnaire was used to determine a summary measure of PAEE, the metabolic equivalent of task (MET), taking into account physical activities related to occupation, recreation, travel, sports, and housework. PAEE was the predictor variable. To assess associations of PAEE with outcomes, the sex-age-specific median MET was used. The malnutrition-inflammation score (MIS) with range of 0 to 30 (higher is worse), conicity index as indicator of abdominal adiposity and C-reactive protein (CRP) were the nutritional-inflammatory outcomes. Results The mean age of the patients was 48.9 ± 13.8 y, 60.3% were males, 16.7% diabetic, 88.1% nonwhite. In multivariable logistic regression models with adjustments for sociodemographic variables and comorbidities, PAEE ≤median was associated with MIS ≥6 (odds ratio [OR] = 1.57; 95% confidence interval [CI] = 1.08, 2.29), conicity index ≥1.3 (OR = 1.52, 95% CI = 1.03, 2.23) and CRP >1.30 mg/dL (OR = 1.69, 95% CI = 1.08, 2.84). Conclusions Greater physical activity assessed by PAEE was associated with indicators of better nutritional and inflammation status. These results indicate opportunities for improving outcomes in MHD patients by counseling and treatment intervention. |
| Databáze: | OpenAIRE |
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