Improved wear performance with crosslinked UHMWPE and zirconia implants in knee simulation

Autor:	Mikio Ogino, Ian C. Clarke, Riichiro Tsukamoto, Hiromu Shoji, Takashi Nakamura, Taiyo Asano, Sam Chen
Rok vydání:	2006
Předmět:	medicine.medical_specialty Surface Properties medicine.medical_treatment Total knee replacement Prosthesis Design Models Biological Weight-Bearing chemistry.chemical_compound Materials Testing medicine Humans Orthopedics and Sports Medicine Femur Cubic zirconia Ceramic Arthroplasty Replacement Knee business.industry General Medicine Polyethylene Arthroplasty Biomechanical Phenomena Surgery chemistry visual_art visual_art.visual_art_medium Lubrication Zirconium Implant Polyethylenes Knee Prosthesis business human activities Biomedical engineering
Zdroj:	Acta Orthopaedica. 77:505-511
ISSN:	1745-3682 1745-3674
DOI:	10.1080/17453670610046479
Popis:	Suggestions for improved wear performance of total knee replacements have included replacement of standard CoCr femoral components with ceramic and replacement of 3.5-Mrad ultra-high molecular weight polyethylene (UHMWPE) inserts with 5- or 7-Mrad UHMWPE inserts. The ceramic materials used clinically have included alumina, zirconia ceramic and oxidized zirconium.We compared both CoCr and zirconia versions of the Bi-Surface knee replacement in a 6-station knee simulator using alpha calf serum for lubrication (20 mg protein per mL) to evaluate the relative bearing performance.We studied the 4-way knee simulation of implant materials: zirconia ceramic, CoCr, 3.5-Mrad UHMWPE, and 7-Mrad UHMWPE. With CoCr femoral components, the 7-Mrad UHMWPE resulted in a 5- to 8-fold reduction in wear compared to the 3.5-Mrad insert. With the 3.5-Mrad insert, the zirconia bearing provided approximately 4-fold wear reduction compared to CoCr. These wear rates with standard UHMWPE were similar to published wear studies on entire knees. With the exception of the CoCr/7-Mrad and ZrO2/3.5-Mrad combinations, the wear differences were statistically significant.The ZrO2/7-Mrad UHMWPE combination gave the best performance, with no measurable wear over the 5.5 million cycle test duration.
Databáze:	OpenAIRE
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