Late-onset Niemann-Pick disease type C overlapping with frontotemporal dementia syndromes: a case report

Autor:	Dániel Bereczki, Tibor Kovács, Dániel Milanovich, Csilla Hornyák, Nóra Balázs
Rok vydání:	2019
Předmět:	0301 basic medicine Male Pediatrics medicine.medical_specialty Neurology Late onset Progressive supranuclear palsy 03 medical and health sciences 0302 clinical medicine mental disorders medicine Dementia Humans Vertical supranuclear gaze palsy Biological Psychiatry Niemann–Pick disease type C business.industry Parkinsonism Niemann–Pick disease type C Niemann-Pick Disease Type C Middle Aged medicine.disease Corticobasal syndrome Neurology and Preclinical Neurological Studies - Short communication eye diseases Pedigree Psychiatry and Mental health 030104 developmental biology Frontotemporal Dementia Neurology (clinical) business 030217 neurology & neurosurgery Frontotemporal dementia
Zdroj:	Journal of Neural Transmission
ISSN:	1435-1463
Popis:	The diagnosis of adult-onset Niemann–Pick disease type C (NPC) could be difficult because its primary symptoms [dementia and vertical supranuclear gaze palsy (VSGP)] are mainly seen in neurodegenerative dementias and progressive supranuclear palsy (PSP). Our patient with dementia and asymmetric parkinsonism resembled corticobasal syndrome and after the appearance of VSGP, the criteria of PSP were fulfilled too. Cerebellar symptoms appeared late during the course of the disease, leading to the diagnosis of NPC at the age of 59 years.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f8096aa69177979c5a6bd42579f591 https://pubmed.ncbi.nlm.nih.gov/31506735 Zobrazit plný text záznamu Full text from SpringerLink