Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: a postmarketing surveillance report

Autor:	Naonobu Sugiyama, Takeshi Kokubo, Yasuo Suzuki, Yuri Fukuma, N. Sugiyama
Rok vydání:	2018
Předmět:	musculoskeletal diseases Adult Male medicine.medical_specialty Health Status Postmarketing surveillance Pharmacology Severity of Illness Index Arthritis Rheumatoid 03 medical and health sciences Young Adult 0302 clinical medicine Rheumatology Japan Risk Factors Internal medicine Product Surveillance Postmarketing Medicine Humans 030212 general & internal medicine skin and connective tissue diseases Aged Retrospective Studies 030203 arthritis & rheumatology Aged 80 and over Dose-Response Relationship Drug business.industry Incidence Middle Aged medicine.disease High dose methotrexate Methotrexate Treatment Outcome Rheumatoid arthritis Antirheumatic Agents Disease Progression Drug Therapy Combination Female business medicine.drug Follow-Up Studies
Zdroj:	Modern rheumatology. 30(1)
ISSN:	1439-7609
Popis:	Objectives: To confirm the safety and effectiveness of high-dose (>8 mg/week) methotrexate (MTX) for the treatment of rheumatoid arthritis in Japan.Methods: A postmarketing surveillance program enr...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f412e195fc25ba4b13c601cc8913ed https://pubmed.ncbi.nlm.nih.gov/28395637 Zobrazit plný text záznamu