Influence of sweeteners in the biodistribution of radiopharmaceutical and laboratory tests in rats
| Autor: | Vanessa Santos de Arruda Barbosa, Christina da Silva Camillo, Juliana Késsia Barbosa Soares, CecÃlia Maria de Carvalho Xavier Holanda, MarÃlia Ferreira Frazão Tavares de Melo, Janette Monroy Osorio, Michelly Pires Queiroz, Aldo Cunha Medeiros, Tarciso Bruno Montenegro Sampaio |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
medicine.medical_specialty Sucralose Biodistribution Bilirubin 01 natural sciences Applied Microbiology and Biotechnology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine 010608 biotechnology Internal medicine Genetics medicine Molecular Biology Sucralose fructose adolescent rats radiopharmaceutical Albumin Fructose Metabolism Endocrinology chemistry 030220 oncology & carcinogenesis Alkaline phosphatase Histopathology Agronomy and Crop Science Biotechnology |
| Zdroj: | African Journal of Biotechnology; Vol 15, No 50 (2016); 2751-2757 |
| ISSN: | 1684-5315 |
| Popis: | This study aimed to evaluate the effect of supplementation of sucralose and fructose on the metabolism of adolescent rats. Eighteen male Wistar rats were divided into 3 groups: control group (GC), fructose group (GF) treated with 50 mg/kg of fructose, and sucralose group (GS) receiving 50 mg/kg of sucralose for 24 days. The weight and feed intake were measured weekly. At the end of the experiment, some biochemical parameters, histopathology of the liver and biodistribution of the radiotracer 99mTc-sodium phytate in liver and blood were analyzed. The GF showed higher body weight only in the first week compared with GS and GC (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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