Inside minds, beneath diseases: social cognition in amyotrophic lateral sclerosis-frontotemporal spectrum disorder
| Autor: | Rafael Aranguiz, Gabriel Cea, Leonardo Cruz de Souza, Andrea Slachevsky, Laura Rousseff, Gada Musa, Leandro Boson Gambogi, Patricia Lillo, Paulo Caramelli, Antônio Lúcio Teixeira, Ricardo Hughes, Luciano Inácio Mariano, Andres Aragon, Daniel Valenzuela, Teresa Parrao, Henrique Cerqueira Guimarães |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Social Cognition medicine.medical_specialty Audiology 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Social cognition Memory span Medicine Humans 0501 psychology and cognitive sciences Spectrum disorder Cognitive Dysfunction Amyotrophic lateral sclerosis Aged business.industry 05 social sciences Amyotrophic Lateral Sclerosis Neuropsychology Cognition Middle Aged medicine.disease Mental Status and Dementia Tests Psychiatry and Mental health Case-Control Studies Frontotemporal Dementia Faux pas Surgery Female Neurology (clinical) business Facial Recognition 030217 neurology & neurosurgery Frontotemporal dementia |
| Zdroj: | Journal of neurology, neurosurgery, and psychiatry. 91(12) |
| ISSN: | 1468-330X |
| Popis: | ObjectiveTo compare social cognition performance between patients with amyotrophic lateral sclerosis (ALS) and those patients with behavioural variant frontotemporal dementia (bvFTD).MethodsWe included 21 participants with ALS, 20 with bvFTD and 21 healthy controls who underwent a comprehensive cognitive battery, including the short version of the Social Cognition and Emotional Assessment (Mini-SEA), which comprises the faux pas test and Facial Emotion Recognition Test (FERT); Mini-Mental State Examination; Frontal Assessment Battery; lexical fluency (F-A-S), category fluency (animals/minute), digit span (direct and backwards) tests and the Hayling test. A post hoc analysis was conducted with the patients with ALS divided into two subgroups: patients without cognitive impairment (ALScn; n=13) and patients with cognitive impairment (ALSci; n=8).ResultsNo significant difference was noted between participant groups in terms of the age, sex and education. ALS-total group and patients with bvFTD had similar disease durations. Patients with ALSci performed poorly when compared with controls with regard to the FERT (pfaux pas (pDiscussionOur findings support a cognitive continuum between ALS and bvFTD and shed light on the cognitive heterogeneity of ALS, expanding its possible neuropsychological profiles. |
| Databáze: | OpenAIRE |
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