Novel glycosylation zinc(II)–cryptolepine complexes perturb mitophagy pathways and trigger cancer cell apoptosis and autophagy in SK-OV-3/DDP cells

Autor:	Zhen Zhou, Ling-Qi Du, Xiao-Mei Huang, Li-Gang Zhu, Qiao-Chang Wei, Qi-Pin Qin, Hedong Bian
Rok vydání:	2022
Předmět:	Ovarian Neoplasms Pharmacology Glycosylation Organic Chemistry Mitophagy Apoptosis Antineoplastic Agents General Medicine Ligands Zinc Coordination Complexes Drug Discovery Autophagy Humans Female Cisplatin
Zdroj:	European Journal of Medicinal Chemistry. 243:114743
ISSN:	0223-5234
Popis:	With the aim of shedding some light on the mechanism of action of zinc(II) complexes in antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc(II)-cryptolepine complexes, i.e., [Zn(QA1)Cl
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d493daa348937472ba6fe1890c9949 https://doi.org/10.1016/j.ejmech.2022.114743 Zobrazit plný text záznamu Full Text from ScienceDirect