Case Report: Overlapping Multiple Sclerosis With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature

Autor: Liang-Yu Zou, Xuejun Fu, Qian Wang, Qianhui Xu, Yaqing Zhang, Ying Huang, Silin Zeng
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
0301 basic medicine
lcsh:Immunologic diseases. Allergy
Psychosis
anti-NMDA antibody
Levetiracetam
Movement disorders
Prednisolone
Immunology
Anti-Inflammatory Agents
Case Report
multiple sclerosis
Methylprednisolone
03 medical and health sciences
Multiple Sclerosis
Relapsing-Remitting
0302 clinical medicine
mental disorders
medicine
Humans
Immunologic Factors
Immunology and Allergy
overlap
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Anti-NMDA receptor encephalitis
business.industry
Multiple sclerosis
musculoskeletal
neural
and ocular physiology
Immunoglobulins
Intravenous
anti-NMDA receptor encephalitis
medicine.disease
atypical symptoms
Pathophysiology
Hypoventilation
030104 developmental biology
nervous system
Olanzapine
NMDA receptor
Anticonvulsants
Female
medicine.symptom
biological phenomena
cell phenomena
and immunity
business
lcsh:RC581-607
030217 neurology & neurosurgery
Encephalitis
psychological phenomena and processes
Antipsychotic Agents
Zdroj: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.595417/full
Popis: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder mediated by NMDAR antibodies, typically manifesting as behavioral complaints, psychosis, seizures, movement disorders, hypoventilation, and autonomic dysfunction. In recent years, the predisposing factors and pathophysiological mechanisms of anti-NMDAR encephalitis have been tried to be clarified. It has been recognized that an overlap may be observed between anti-NMDAR encephalitis and inflammatory demyelinating disease. However, anti-NMDAR encephalitis is rarely associated with multiple sclerosis. Here, we describe a Chinese female patient diagnosed with relapsing remitting multiple sclerosis who developed anti-NMDAR encephalitis. Further, we discuss the previously reported literature.
Databáze: OpenAIRE
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