Regenerative Medicine Under the Control of 3D Scaffolds: Current State and Progress of Tissue Scaffolds
| Autor: | Fatemeh Sadegian, Bahareh Porjabbar, Javad Ranjbari, Parviz Ranjbarvan, Simzar Hosseinzadeh, Nasim Salehi-Nik, Ali Golchin, Masoumeh Estaji, Sina Farzaneh, Mohammad Kanafimahbob |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Scaffold Tissue Engineering Tissue Scaffolds Chemistry Cell Medicine (miscellaneous) Biomaterial Biocompatible Materials Nanotechnology General Medicine Cell fate determination Regenerative Medicine Regenerative medicine Extracellular Matrix Extracellular matrix 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure Tissue engineering 030220 oncology & carcinogenesis medicine Humans Stem cell |
| Zdroj: | Current Stem Cell Research & Therapy. 16:209-229 |
| ISSN: | 1574-888X |
| DOI: | 10.2174/1574888x15666200720115519 |
| Popis: | Currently, combining stem cells (SCs) with biomaterial scaffolds provides a promising strategy for the future of biomedicine and regenerative medicine (RG). The cells need similar substrates of the extracellular matrix (ECM) for normal tissue development, which signifies the importance of three dimensional (3D) scaffolds to determine cell fate. Herein, the importance and positive contributions of corresponding 3D scaffolds on cell functions, including cell interactions, cell migrations, and nutrient delivery, are presented. Furthermore, the synthesis techniques which are recruited to fabricate the 3D scaffolds are discussed, and the related studies of 3D scaffold for different tissues are also reported in this paper. This review focuses on 3D scaffolds that have been used for tissue engineering purposes and directing stem cell fate as a means of producing replacements for biomedical applications. |
| Databáze: | OpenAIRE |
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