Population-based study on the seroprevalence of hepatitis A, B, and C virus infection in Amsterdam, 2004
Autor: | Gerard J.B. Sonder, R. A. Coutinho, Nicole H. T. M. Dukers, G.G.G. Baaten, J. A. R. Van Den Hoek |
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Přispěvatelé: | Infectious diseases, AII - Amsterdam institute for Infection and Immunity |
Rok vydání: | 2007 |
Předmět: |
Adult
Male Adolescent Antibodies Viral medicine.disease_cause Orthohepadnavirus Risk Factors Seroepidemiologic Studies Virology medicine Humans Seroprevalence Aged Netherlands Hepatitis Hepatitis B virus biology business.industry Hepatitis A Hepatitis C Middle Aged Hepatitis B medicine.disease biology.organism_classification Infectious Diseases Population Surveillance Female Viral hepatitis business |
Zdroj: | Journal of medical virology, 79(12), 1802-1810. Wiley-Liss Inc. |
ISSN: | 1096-9071 0146-6615 |
Popis: | In order to enhance screening and preventive strategies, this study investigated the seroprevalence of hepatitis A, B, and C in the general adult urban population and in subgroups. In 2004, sera from 1,364 adult residents of Amsterdam were tested for viral markers. Sociodemographic characteristics were collected using a standardized questionnaire. For hepatitis A, 57.0% was immune. Of first-generation immigrants from Turkey and Morocco, 100% was immune. Of all Western persons and second-generation non-Western immigrants, approximately half was still susceptible. For hepatitis B, 9.9% had antibodies to hepatitis B core antigen (anti-HBc) and 0.4% had hepatitis B surface antigen. Anti-HBc seroprevalences were highest among first-generation immigrants from Surinam, Morocco, and Turkey, and correlated with age at the time of immigration, and among men with a sexual preference for men. Seroprevalence among second-generation immigrants was comparable to Western persons. The seroprevalence of hepatitis C virus antibodies was 0.6%. In conclusion, a country with overall low endemicity for viral hepatitis can show higher endemicity in urban regions, indicating the need for differentiated regional studies and prevention strategies. More prevention efforts in cities like Amsterdam are warranted, particularly for hepatitis A and B among second-generation immigrants, for hepatitis B among men with a sexual preference for men, and for hepatitis C. Active case finding strategies are needed for both hepatitis B and C. |
Databáze: | OpenAIRE |
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