Influence of arteriographic contrast media on the Na+/Ca++-ratio in blood
| Autor: | W. Schröter, H. G. Wolpers, J. Zipfel, D. Baller, Gerhard Hellige, Ensink Fb |
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| Rok vydání: | 1981 |
| Předmět: |
Pathology
medicine.medical_specialty Sodium Contrast Media chemistry.chemical_element Electrolyte 030204 cardiovascular system & hematology Calcium Coronary Angiography 030218 nuclear medicine & medical imaging Contractility 03 medical and health sciences 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Chelation Chelating Agents Calcium metabolism business.industry Angiography Coronary arteriography Myocardial Contraction In vitro 3. Good health chemistry Depression Chemical Biophysics Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiovascular and Interventional Radiology. 4:8-13 |
| ISSN: | 1432-086X 0174-1551 |
| DOI: | 10.1007/bf02552399 |
| Popis: | To investigate the basis of cardiodepressive side effects in coronary arteriography, the isolated effects of different contrast media on electrolyte levels in blood (and blood fractions) were quantified in vitro. Due to their sodium content and calcium chelation, ionic media cause an imbalance in the extracellar Na+/Ca++-ratio that determines myocardial contractility. Ca++-chelation exceeded that due to stabilizing additives indicating a binding by the contrast agents themselves. The amount of calcium bound varied with different media and was greatest with Renografin. It is suggested that the degree of Na+/Ca++-imbalance in blood explains the extent of acute cardiodepression. |
| Databáze: | OpenAIRE |
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