Percutaneous Core Needle Biopsy in Retroperitoneal Sarcomas Does Not Influence Local Recurrence or Overall Survival
Autor: | Andrew J. Hayes, J. L. Martin, Aadil A. Khan, Dirk C. Strauss, J.M. Thomas, Michelle J. Wilkinson |
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Rok vydání: | 2014 |
Předmět: |
Adult
Male medicine.medical_specialty Percutaneous Adolescent Abdominal wall Young Adult Biopsy Site Surgical oncology Biopsy medicine Humans Prospective Studies Retroperitoneal Neoplasms Prospective cohort study Survival rate Aged Neoplasm Staging Aged 80 and over medicine.diagnostic_test business.industry Sarcoma Middle Aged Prognosis medicine.disease Surgery Survival Rate medicine.anatomical_structure Oncology Female Biopsy Large-Core Needle Neoplasm Grading Neoplasm Recurrence Local business Follow-Up Studies |
Zdroj: | Annals of Surgical Oncology. 22:853-858 |
ISSN: | 1534-4681 1068-9265 |
Popis: | Tumours within the retroperitoneum can cause a diagnostic dilemma. A preoperative core needle biopsy often is required to establish a histological diagnosis. Preoperative core needle biopsy for extremity soft-tissue sarcoma is oncologically safe and biopsy site recurrence is extremely rare, attributed to placing the biopsy site within the planned resection field. This study investigates whether preoperative core needle biopsy affects oncological outcomes in retroperitoneal sarcomas. Patients undergoing resection of intermediate- and high-grade primary retroperitoneal sarcoma from 1990 until 2011 were included. Primary endpoints were immediate biopsy-related complications, local recurrence, and overall survival. A total of 150 patients were included in the analysis. Of these, 90 patients underwent resection after a preoperative biopsy. Median follow-up was 48 months. One patient required hospital admission postbiopsy for an abdominal wall rectus sheath haematoma. No patient developed intra-abdominal complications that required hospitalisation or early operation related to core needle biopsy. No patient developed a biopsy site recurrence. There was no significant increase in either local recurrence (p = 0.101) or overall survival (p = 0.191) after core needle biopsy. Preoperative core needle biopsy for retroperitoneal sarcomas is safe and does not affect oncological outcome. |
Databáze: | OpenAIRE |
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