Leiomyosarcoma of the Tongue With Multiple Metastases: A Case Report and Review of Literature
| Autor: | John HyunBaek Ahn, Tahir Mirza, Phillip Ameerally |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Leiomyosarcoma
medicine.medical_specialty Lung Neoplasms Palliative care medicine.medical_treatment Bone Neoplasms Soft Tissue Neoplasms Tongue Antineoplastic Combined Chemotherapy Protocols medicine Humans Ifosfamide Antineoplastic Agents Alkylating Muscle Neoplasms Chemotherapy Antibiotics Antineoplastic Lung business.industry Palliative Care Soft tissue Middle Aged medicine.disease Tongue Neoplasms Surgery medicine.anatomical_structure Otorhinolaryngology Doxorubicin Primary Leiomyosarcoma Female Oral Surgery business medicine.drug |
| Zdroj: | Journal of Oral and Maxillofacial Surgery. 70:1745-1750 |
| ISSN: | 0278-2391 |
| DOI: | 10.1016/j.joms.2011.06.201 |
| Popis: | Leiomyosarcoma of the tongue is an extremely rare malignant mesenchymal neoplasm and only 25 cases have been described in the English-language literature, 22 of which were primary lesions. A case is presented of a 54-year-old female patient diagnosed with primary leiomyosarcoma of the tongue with lung and multiple soft tissue metastases. This case is especially unusual because widespread soft tissue metastases resulted, involving the lung and skeletal muscle in 3 separate sites. Unfortunately, curative treatment was not possible. Chemotherapy using a combination of ifosfamide and doxorubicin was, therefore, provided as palliation, with a good response after a 3-week cycle of therapy. Currently available literature on primary and secondary leiomyosarcoma of the tongue was reviewed for a better understanding of this rare mesenchymal neoplasm. To the investigators' knowledge, there are no other reported cases in the literature that have previously been managed with chemotherapy alone. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|