Interindividual Variability in Biomarkers of Cardiometabolic Health after Consumption of Major Plant-Food Bioactive Compounds and the Determinants Involved
| Autor: | Dragan Milenkovic, Ana Rodriguez-Mateos, Francisco A. Tomás-Barberán, Jose M. Ordovas, Christine Morand, Aedin Cassidy, Paul A. Kroon, Aleksandra Konić-Ristić, Raffaele De Caterina |
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| Přispěvatelé: | Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, Department of Nutrition and Preventive Medicine, Norwich Medical School, University of East Anglia, School of Food Science and Nutrition, University of Leeds, Research Group on Quality, Safety and Bioactivity of Plant Foods, Centro de Edafologia y Biologia Aplicada del Segura, Nutrition and Genomics Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University [Medford], Food and Health Programme, Institute of Food Research, Norwich Research Park, Institute of Clinical Physiology, National Council of Research, Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University of Dusseldorf, COST (European Cooperation in Science and Technology), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), University of East Anglia [Norwich] (UEA), Heinrich Heine Universität Düsseldorf = Heinrich Heine University [Düsseldorf] |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male and promotion of well-being obesity biological responsiveness Phytochemicals Medicine (miscellaneous) Type 2 diabetes Health benefits Plant foods Cardiovascular human health Oral and gastrointestinal interindividual variability chemistry.chemical_compound Risk Factors cardiovascular disease maladie cardiovasculaire Cause of death Randomized Controlled Trials as Topic 2. Zero hunger Metabolic Syndrome Nutrition and Dietetics syndrome métabolique metabolic x syndrome santé humaine Bioactive compound 3. Good health Stroke obésité Cardiovascular Diseases Female variabilité inter individuelle Type 2 cardiometabolic health diabète de type 2 aliment d'origine végétale Reviews Biology Health outcomes 03 medical and health sciences Sex Factors determinants of interindividual variability Genetic SDG 3 - Good Health and Well-being Environmental health medicine Diabetes Mellitus Humans Obesity Polymorphism 3.3 Nutrition and chemoprevention Metabolic and endocrine Nutrition 030109 nutrition & dietetics Polymorphism Genetic business.industry Polyphenols medicine.disease Prevention of disease and conditions type ii diabetes Biotechnology Good Health and Well Being chemistry Diabetes Mellitus Type 2 plant-food bioactives Metabolic syndrome business [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition Biomarkers Food Science |
| Zdroj: | Advances in Nutrition Advances in Nutrition, Oxford University Press, 2017, 8 (4), pp.558-570. ⟨10.3945/an.116.013623⟩ Milenkovic, D, Morand, C, Cassidy, A, Konic-Ristic, A, Tomás-Barberán, F, Ordovas, J M, Kroon, P, De Caterina, R & Rodriguez-Mateos, A 2017, ' Interindividual Variability in Biomarkers of Cardiometabolic Health after Consumption of Major Plant-Food Bioactive Compounds and the Determinants Involved ', Advances in Nutrition, vol. 8, no. 4, pp. 558-570 . https://doi.org/10.3945/an.116.013623 Advances in Nutrition, 2017, 8 (4), pp.558-570. ⟨10.3945/an.116.013623⟩ Advances in nutrition (Bethesda, Md.), vol 8, iss 4 |
| ISSN: | 2161-8313 2156-5376 |
| DOI: | 10.3945/an.116.013623⟩ |
| Popis: | We acknowledge networking support by the COST Action FA 1403 POSITIVe (interindividual variation in response to consumption of plant food bioactives and determinants involved), supported by COST (European Cooperation in Science and Technology); Cardiometabolic disease, comprising cardiovascular diseases, type 2 diabetes, and their associated risk factors including metabolic syndrome and obesity, is the leading cause of death worldwide. Plant foods are rich sources of different groups of bioactive compounds, which might not be essential throughout life but promote health and well-being by reducing the risk of age-related chronic diseases. However, heterogeneity in the responsiveness to bioactive compounds can obscure associations between their intakes and health outcomes, resulting in the hiding of health benefits for specific population groups and thereby limiting our knowledge of the exact role of the different bioactive compounds for health. The heterogeneity in response suggests that some individuals may benefit more than others from the health effects of these bioactive compounds. However, to date, this interindividual variation after habitual intake of plant bioactive compounds has been little explored. The aim of this review is to provide an overview of the existing research that has revealed interindividual variability in the responsiveness to plant-food bioactive compound consumption regarding cardiometabolic outcomes, focusing on polyphenols, caffeine and plant sterols, and the identified potential determinants involved. |
| Databáze: | OpenAIRE |
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