Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells

Autor: J.B. Kaper, Ilan Rosenshine, M S Donnenberg, B. Brett Finlay
Rok vydání: 1992
Předmět:
Zdroj: Europe PubMed Central
ISSN: 1098-5522
0019-9567
DOI: 10.1128/iai.60.6.2541-2543.1992
Popis: The cytoskeletal lesions associated with enteropathogenic Escherichia coli adhering to cultured HeLa epithelial cells were examined by immunofluorescence microscopy. The microfilament-associated proteins actin, alpha-actinin, talin, and ezrin were localized with adherent enteropathogenic E. coli, whereas tropomyosin, keratin and vimentin (intermediate filaments), tubulin (microtubules), and vinculin were not localized. These cytoskeletal structures differed significantly from those associated with Salmonella typhimurium internalization (invasion).
Databáze: OpenAIRE